homeabout uscontact us

 

Tutorial 2: Step 6 Perform Hierarchical Clustering

 

Perform Hierarchical Clustering

1. Click the 3-nearest neighbors dataset in the Experiments navigator (Click the Experiments tab to display the Experiments navigator). The item is highlighted.

2. Click the Hierarchical Clustering toolbar icon , or select Hierarchical Clustering from the Clustering menu, or right-click the item and select Hierarchical Clustering from the shortcut menu. The Hierarchical Clustering dialog is displayed.

3. Set parameters.

Parameter

Setting

Clustering Orientation

Cluster Samples

Data Measurements: Between Data Points

Pearson Correlation

Data Measurements: Between Clusters

Average Linkage

4. Click OK. The clustering operation is performed, and upon successful completion, a new Sample Hierarchical Clustering experiment is added to the Experiments navigator under the original dataset.

GeneLinkerô provides many different clustering algorithms, and there are other clustering methods listed under Partitional Clustering. Genes can be clustered in addition to samples by using the same command sequence as above but changing the choice of clustering orientation from Samples to Genes.

If you have automatic visualizations enabled in your user preferences, a matrix tree plot of the clustering results is displayed.